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Article

BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth

1 Apr 2023

Abstract excerpt

Clinical evidence points to a function for B cell-activating factor (BAFF) in pregnancy. However, direct roles for BAFF-axis members in pregnancy have not been examined. Here, via utility of genetically modified mice, we report that BAFF promotes inflammatory responsiveness and increases susceptibility to inflammation-induced preterm birth (PTB). In contrast, we show that the closely related A...

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Share to Pregnancy and preeclampsia studies
Share to Preterm Birth and Chorioamnionitis
Share to Reproductive System and Pregnancy

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Identifiers

PMID: 37027297
DOI: 10.1016/j.celrep.2023.112352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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