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Article

Human papillomavirus and p53 mutations in head and neck squamous cell carcinoma among Japanese population.

Cancer science - 1 Apr 2014

Maruyama Hiromi, Yasui Toshimichi, Ishikawa-Fujiwara Tomoko, Morii Eiichi, Yamamoto Yoshifumi, Yoshii Tadashi, Takenaka Yukinori, Nakahara Susumu, Todo Takeshi, Hongyo Tadashi, Inohara Hidenori

Abstract excerpt

We aimed to reveal the prevalence and pattern of human papillomavirus (HPV) infection and p53 mutations among Japanese head and neck squamous cell carcinoma (HNSCC) patients in relation to clinicopathological parameters. Human papillomavirus DNA and p53 mutations were examined in 493 HNSCCs and its subset of 283 HNSCCs. Oropharyngeal carcinoma was more frequently HPV-positive than non-oropharyngeal carcinoma...

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Identifiers

PMID: 24521534
DOI: 10.1111/cas.12369
PMCID: PMC4317800

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