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Article

Relationships between p53 mutation, HPV status and outcome in oropharyngeal squamous cell carcinoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Feb 2016

Hong Angela, Zhang Xiaoying, Jones Deanna, Veillard Anne-Sophie, Zhang Mei, Martin Andrew, Lyons J Guy, Lee C Soon, Rose Barbara

Abstract excerpt

BACKGROUND AND PURPOSE: This study aimed to examine the rate and type of p53 mutation in oropharyngeal cancer (OSCC). Relationships were sought between human papillomavirus (HPV) status and p53 mutation. The role of p53 mutation as a prognostic factor independent of HPV status and as a modifier of the effect of HPV on outcomes was also examined. METHODS: The HPV status of 202 cases was determined by HPV DNA by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26952933
DOI: 10.1016/j.radonc.2016.02.009

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