Targeting Mutated p53: Naivete and Enthusiasm to Attempt the Impossible.

Abstract excerpt

Tumor suppressor TP53 is an important gene in human cancer because it is mutated in the majority of tumors, leading to loss-of-function or gain-of-function phenotypes. Mutated TP53 acts like an oncogene, driving cancer progression and causing poor patient outcomes. The role of mutated p53 in cancer has been known for over three decades, yet there is no FDA-approved drug to address the problem. This brief...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to TP53 gene
• Share to Mutation
• Share to Neoplasms