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Article

Dysregulation of Histone Acetyltransferases and Deacetylases in Cardiovascular Diseases

1 Jan 2014

Abstract excerpt

Cardiovascular disease (CVD) remains a leading cause of mortality worldwide despite advances in its prevention and management. A comprehensive understanding of factors which contribute to CVD is required in order to develop more effective treatment options. Dysregulation of epigenetic posttranscriptional modifications of histones in chromatin is thought to be associated with the pathology of many disease models,...

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PMID: 24693336
DOI: 10.1155/2014/641979

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