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Cardiometabolic drugs and kidney function – a drug target Mendelian randomisation study

2025-06-17

Abstract excerpt

<h4>Background</h4> Chronic kidney disease (CKD) is a growing global public health concern. Using drug target Mendelian randomization (MR) approach, we assessed the effects of cardiometabolic drug classes on kidney function indices in the general population. <h4>Method</h4> We leveraged 93 single nucleotide polymorphisms (SNPs) as genetically proxies for targets of antihypertensives (Ca-channel blockers/CCB, beta-...

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Literature Corpus work
717f5762-1d05-5deb-8e01-b9dced3836af
DOI
10.1101/2025.06.16.25329403
Open publication

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Cardiometabolic drugs and kidney function – a drug target Mendelian randomisation studyDOI 10.1101/2025.06.16.25329403
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