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Article

Causal relationship between antihypertensive drugs and Hashimoto's thyroiditis: a drug-target Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Cui Bing, Chen Aqin, Xu Chengcheng, Mao Chaoming, Chen Yuehua

Abstract excerpt

Introduction and objectives: Recent studies have indicated a potential association of hypertension with Hashimoto's thyroiditis (HT) and other autoimmune diseases, yet the impact of antihypertensive drugs on HT risk is not well understood. Methods: We employed a drug-target Mendelian randomization approach to investigate the prolonged impact of 9 classes of antihypertensive medications on HT susceptibility in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39435355
DOI: 10.3389/fendo.2024.1419346
PMCID: PMC11491371

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