Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WGE: a CRISPR database for genome engineering

14 May 2015

Abstract excerpt

UNLABELLED: The rapid development of CRISPR-Cas9 mediated genome editing techniques has given rise to a number of online and stand-alone tools to find and score CRISPR sites for whole genomes. Here we describe the Wellcome Trust Sanger Institute Genome Editing database (WGE), which uses novel methods to compute, visualize and select optimal CRISPR sites in a genome browser environment. The WGE database currently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biotechnology and Related Fields
Share to CRISPR and Genetic Engineering
Share to Genetic Neurodegenerative Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25979474
DOI: 10.1093/bioinformatics/btv308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WGE: a CRISPR database for genome engineeringPMID 25979474Read ↗

CRISPR-detector: fast and accurate detection, visualization, and annotation of genome-wide mutations induced by genome editing events.Semantic proximity Read ↗

dbGuide: A database of functionally validated guide RNAs for genome editing in human and mouse cellsSemantic proximity Read ↗

Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).Semantic proximity Read ↗

CasFinder: Flexible algorithm for identifying specific Cas9 targets in genomesSemantic proximity Read ↗

CRISPRseek: a bioconductor package to identify target-specific guide RNAs for CRISPR-Cas9 genome-editing systems.Semantic proximity Read ↗

Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screensSemantic proximity Read ↗

CRISPR-Detector: Fast and Accurate Detection, Visualization, and Annotation of Genome-Wide Mutations Induced by Gene Editing EventsSemantic proximity Read ↗

GenEditID: an open-access platform for the high-throughput identification of CRISPR edited cell clonesSemantic proximity Read ↗

GUIDES: sgRNA design for loss-of-function screensSemantic proximity Read ↗

SNP-CRISPR: a web tool for SNP-specific genome editingSemantic proximity Read ↗

Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seqSemantic proximity Read ↗

A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.