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Septin-3 autoimmunity in patients with paraneoplastic cerebellar ataxia

30 Mar 2023

Abstract excerpt

BACKGROUND: Septins are cytoskeletal proteins with filament forming capabilities, which have multiple roles during cell division, cellular polarization, morphogenesis, and membrane trafficking. Autoantibodies against septin-5 are associated with non-paraneoplastic cerebellar ataxia, and autoantibodies against septin-7 with encephalopathy with prominent neuropsychiatric features. Here, we report on newly...

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PMID: 36997937
DOI: 10.1186/s12974-023-02718-9

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