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Article

Cyclin-dependent kinase 5 phosphorylation of human septin SEPT5 (hCDCrel-1) modulates exocytosis.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Apr 2008

Amin Niranjana D, Zheng Ya-Li, Kesavapany Sashi, Kanungo Jyotshnabala, Guszczynski Tad, Sihag Ram K, Rudrabhatla Parvathi, Albers Wayne, Grant Philip, Pant Harish C

Abstract excerpt

Cyclin-dependent kinase 5 (Cdk5) is predominantly expressed in the nervous system, where it is involved in neuronal migration, synaptic transmission, and survival. The role of Cdk5 in synaptic transmission is mediated by regulating the cellular functions of presynaptic proteins such as synapsin, Munc18, and dynamin 1. Its multifunctional role at the synapse is complex and probably involves other novel substrates....

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Identifiers

PMID: 18385322
DOI: 10.1523/JNEUROSCI.0453-08.2008
PMCID: PMC6671095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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