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Article

Distinctive hematological abnormalities in East Asian neonates and children with Down syndrome.

International journal of laboratory hematology - 1 Aug 2011

Kim D-W, Kim H-R, Shin M-G, Baek H-J, Kook H, Hwang T-J, Shin J-H, Suh S-P, Ryang D-W

Abstract excerpt

INTRODUCTION: Neonates with Down syndrome (DS) are predisposed to developing transient abnormal myelopoiesis (TAM) and acute myeloid leukemia (AML) associated with DS. However, there is a paucity of data on hematological aberrations and GATA1 mutations in neonates with DS in East Asian populations. METHODS: Total 109 patients with DS who had one or more CBCs obtained were enrolled. The molecular analysis of the...

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Asia, Eastern
Down Syndrome
GATA1 Transcription Factor
Hematologic Diseases
Infant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant, Newborn

Leukemia, Myeloid, Acute

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Identifiers

PMID: 21692995
DOI: 10.1111/j.1751-553X.2011.01299.x

Genes

GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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