MicroRNA regulate immune pathways in T-cells in multiple sclerosis (MS)

Abstract excerpt

BACKGROUND: MicroRNA are small noncoding RNA molecules that are involved in the control of gene expression. To investigate the role of microRNA in multiple sclerosis (MS), we performed genome-wide expression analyses of mRNA and microRNA in T-cells from MS patients and controls. METHODS: Heparin-anticoagulated peripheral blood was collected from MS-patients and healthy controls followed by isolation of T-cells....

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