Article
Variants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity.
International journal of molecular sciences - 24 Aug 2015
Kiselev Ivan, Bashinskaya Vitalina, Kulakova Olga, Baulina Natalia, Popova Ekaterina, Boyko Alexey, Favorova Olga
Abstract excerpt
Multiple sclerosis (MS) is an autoimmune neuro-inflammatory disease arising from complex interactions of genetic, epigenetic, and environmental factors. Variations in genes of some microRNAs--key post-transcriptional regulators of many genes--can influence microRNAs expression/function and contribute to MS via expression changes of protein-coding target mRNA genes. We performed an association study of...
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