Article
miRNA profiling for biomarker discovery in multiple sclerosis: from microarray to deep sequencing.
Journal of neuroimmunology - 15 Jul 2012
Guerau-de-Arellano Mireia, Alder Hansjuerg, Ozer Hatice Gulcin, Lovett-Racke Amy, Racke Michael K
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level. miRNAs are highly expressed in cells of the immune and nervous system, attesting to their importance in Neuroimmunology. Besides their involvement in modulation of physiological and pathological processes, miRNAs hold high promise as disease biomarkers, therapeutic agents and/or drug targets. Several...
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