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Article

Convergent analysis of genome‐wide genotyping and transcriptomic data suggests association of zinc finger genes with lithium response in bipolar disorder

1 Oct 2018

Abstract excerpt

Lithium is the mainstay treatment in bipolar disorder (BD) for its effectiveness in the acute phases of illness and in prevention of recurrences. Lithium's mechanism of action is complex, and while it modulates the function of hundreds of molecular targets, most of these effects could be unspecific and not relevant for its clinical efficacy. In this study, we applied an integrated analytical approach using...

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PMID: 30318722
DOI: 10.1002/ajmg.b.32663

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