Article
Prognostic Value of KRAS Exon-specific Mutations in Patients With Colorectal Cancer.
Anticancer research - 1 Apr 2023
Asako Kentaro, Hayama Tamuro, Hashiguchi Yojiro, Miyata Toshiya, Fukushima Yoshihisa, Shimada Ryu, Kaneko Kensuke, Nozawa Keijiro, Matsuda Keiji, Fukagawa Takeo
Abstract excerpt
BACKGROUND/AIM: The clinical significance of many RAS-family mutations in colorectal cancer (CRC) remains unclear. The purpose of this study was to investigate the relationship of RAS mutations on an exon basis (i.e., mutations in KRAS exons 2, 3, and 4 and in NRAS) with clinicopathological features and prognosis in CRC. PATIENTS AND METHODS: We performed a retrospective cohort study of the medical records and...
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