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Article

Mutation spectra of RAS gene family in colorectal cancer.

American journal of surgery - 1 Sept 2016

Chang Yu-Yao, Lin Pei-Ching, Lin Hung-Hsin, Lin Jen-Kou, Chen Wei-Shone, Jiang Jeng-Kai, Yang Shung-Haur, Liang Wen-Yih, Chang Shih-Ching

Abstract excerpt

BACKGROUND: The clinicopathologic features and frequency of KRAS mutations in colorectal cancer (CRC) patients have been reported; however, the characteristics and impact of NRAS and HRAS mutations on the survival of CRC patients have seldom been addressed. METHODS: Under institutional review board approval, 1,519 CRC patients who underwent surgery were enrolled. Mutation status of RAS was determined by...

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Source

Identifiers

PMID: 27394063
DOI: 10.1016/j.amjsurg.2016.02.013

Genes

NRAS
HRAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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