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Article

Detection of IDH1 Mutation in cfDNA and Tissue of Adult Diffuse Glioma with Allele-Specific qPCR.

Asian Pacific journal of cancer prevention : APJCP - 1 Mar 2023

Husain Adil, Mishra Sridhar, Siddiqui Mohammed Haris, Husain Nuzhat

Abstract excerpt

BACKGROUND: The World Health Organization (WHO) classification of central nervous system (CNS) tumors necessitates testing of isocitrate dehydrogenase (IDH) 1/2 gene mutation in patients with adult-type diffuse glioma (ADG) for better disease management. In clinical practice, the testing of IDH1 is primarily achieved using immunohistochemistry (IHC) specific to IDH1-R132, which carries a sensitivity of 80% and...

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Identifiers

PMID: 36974551
DOI: 10.31557/APJCP.2023.24.3.961
PMCID: PMC10334107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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