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Article

[Analysis of gene mutation profile of adult soft tissue sarcomas using high-throughput sequencing technology].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Sept 2020

Xu S F, Wang W W, Chen J, Liu T, Zhang X X, Xu L B, Zhao Z G, Yu S J, Guo L X

Abstract excerpt

Objective: To understand the genetic variation of soft tissue sarcomas, and to provide a scientific evidence for the individualized treatment. Methods: The somatic mutation and germline mutation of 45 adult soft tissue sarcomas had been detected by high-throughput sequencing technology, the clinical data were also analyzed. Results: A total of 88 gene mutations were detected in 45 samples, including 78 single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32988156
DOI: 10.3760/cma.j.cn112152-20200425-00378

Genes

CDKN2A
CDK4
MDM2
NF1
PTEN
MDM4
TP53
RB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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