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Article

CYP3A5 Polymorphism in Renal Transplantation: A Key to Personalized Immunosuppression.

Transplantation proceedings - 1 Jun 2023

Pasari Amit S, Balwani Manish R, Gurjar Prasad, Bawankule Charulata, Bhawane Amol, Tolani Priyanka, Kashiv Pranjal, Dubey Shubham, Katekhaye Vijay M

Abstract excerpt

BACKGROUND: Tacrolimus is essential for the maintenance of immunosuppression after a kidney transplant. CYP3A5 is the gene that metabolizes tacrolimus, and polymorphism in this gene affects the metabolizing status. AIM: To assess the genetic polymorphism status of patients undergoing kidney transplantation and determine its impact on graft function and complications in the post-transplant period. METHODS: We...

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Cytochrome P-450 CYP3A
Graft Rejection
Immunosuppression Therapy
Immunosuppressive Agents
Kidney Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Polymorphism, Single Nucleotide

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PMID: 36973144
DOI: 10.1016/j.transproceed.2023.02.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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