Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer.

doi:10.1080/2162402X.2023.2189823

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Article

Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer.

Oncoimmunology - 1 Jan 2023

Carbonnier Vincent, Le Naour Julie, Bachelot Thomas, Vacchelli Erika, André Fabrice, Delaloge Suzette, Kroemer Guido

Abstract excerpt

Formyl peptide receptor-1 (FPR1) is a pathogen recognition receptor involved in the detection of bacteria, in the control of inflammation, as well as in cancer immunosurveillance. A single nucleotide polymorphism in FPR1, rs867228, provokes a loss-of-function phenotype. In a bioinformatic study performed on The Cancer Genome Atlas (TCGA), we observed that homo-or heterozygosity for rs867228 in FPR1 (which affects...

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PMID: 36970071
DOI: 10.1080/2162402X.2023.2189823
PMCID: PMC10038022

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