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Article

TYK2 single-nucleotide variants associated with the severity of COVID-19 disease.

Archives of virology - 23 Mar 2023

Zabihi Rizi Fateme, Ghorbani Atousa, Zahtab Parnia, Darbaghshahi Niloufar Naderi, Ataee Nioosha, Pourhamzeh Pardis, Hamzei Behnaz, Dolatabadi Nasrin Fatahi, Zamani Atefeh, Hooshmand Masoud

Abstract excerpt

Coronavirus disease 2019 (COVID-19) is a lethal disease caused by the coronavirus SARS-CoV-2, which can result in a broad clinical spectrum of respiratory symptoms. While many clinical risk factors such as concomitant chronic diseases play roles in the pathophysiology of COVID-19, genetic predisposition factors have not been widely studied. The aim of this study was, therefore, to evaluate the relationship...

Topics

Humans
Angiotensin-Converting Enzyme 2
TYK2 Kinase
COVID-19
SARS-CoV-2
Genotype
Genetic Predisposition to Disease
Polymorphism, Single Nucleotide

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 36959416
DOI: 10.1007/s00705-023-05729-2
PMCID: PMC10035968

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36959416-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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