Article
Genome-wide epistasis study highlights genetic interactions influencing severity of COVID-19.
European journal of epidemiology - 1 Aug 2023
Lin Shiqi, Gao Xingjian, Degenhardt Frauke, Qian Yu, Liu Tianzi, Ramon Xavier Farre, Hadi Syed Sibte, Romero-Gómez Manuel, Fernández Javier, Albillos Agustín, Ferret Maria Buti, Bujanda Luis, Julià Antonio, de Cid Rafael, Asselta Rosanna, Franke Andre, Liu Fan
Abstract excerpt
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to life-threatening respiratory symptoms. Understanding the genetic basis of the prognosis of COVID-19 is important for risk profiling of potentially severe symptoms. Here, we conducted a genome-wide epistasis study of COVID-19 severity in 2243 patients with severe symptoms and 12,612 patients...
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