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Article

Association of genetic variations in ACE2, TIRAP and factor X with outcomes in COVID-19.

PloS one - 1 Jan 2022

Traets Marissa J M, Nijhuis Roel H T, Morré Servaas A, Ouburg Sander, Remijn Jasper A, Blok Bastiaan A, de Laat Bas, Jong Eefje, Herder Gerarda J M, Fiolet Aernoud T L, Verweij Stephan P

Abstract excerpt

BACKGROUND: Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can manifest with varying disease severity and mortality. Genetic predisposition influences the clinical course of infectious diseases. We investigated whether genetic polymorphisms in candidate genes ACE2, TIRAP, and factor X are associated with clinical outcomes in COVID-19. METHODS: We...

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Identifiers

PMID: 34995294
DOI: 10.1371/journal.pone.0260897
PMCID: PMC8740962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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