Article
The role of SIRT1 level and SIRT1 gene polymorphisms in optic neuritis patients with multiple sclerosis.
Orphanet journal of rare diseases - 22 Mar 2023
Kubiliute Aleksandra, Gedvilaite Greta, Vilkeviciute Alvita, Kriauciuniene Loresa, Bruzaite Akvile, Zaliuniene Dalia, Liutkeviciene Rasa
Abstract excerpt
THE AIM: To investigate the role of Sirtuin 1 (SIRT1) level and SIRT1 (rs3818292, rs3758391, rs7895833) gene polymorphisms in patients with optic neuritis (ON) and multiple sclerosis (MS). METHODS: 79 patients with ON and 225 healthy subjects were included in the study. ON patients were divided into 2 subgroups: patients with MS (n = 30) and patients without MS (n = 43). 6 ON patients did not have sufficient data...
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