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Article

Significant Association of rs77493513 Polymorphism in 3'-UTR of the NRG1 Gene with the Risk of Multiple Sclerosis Disease.

Metabolic brain disease - 1 Apr 2022

Ghorbani Maedeh, Mohamadynejad Parisa, Moghanibashi Mehdi

Abstract excerpt

Multiple sclerosis (MS) is a chronic inflammatory and autoimmune disease characterized by demyelination of the central nervous system (CNS). Neuregulin 1 (NRG1) is a signaling protein that plays an important role in a variety of biological processes, including potentiate oligodendrocyte differentiation and myelination in the CNS, immune response regulation, and inflammation. Single nucleotide polymorphism (SNP)...

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PMID: 35106689
DOI: 10.1007/s11011-022-00922-9

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