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Article

Association of VEGFA, TIMP-3, and IL-6 gene polymorphisms with predisposition to optic neuritis and optic neuritis with multiple sclerosis.

Ophthalmic genetics - 1 Feb 2021

Punyte Vaida, Vilkeviciute Alvita, Gedvilaite Greta, Kriauciuniene Loresa, Liutkeviciene Rasa

Abstract excerpt

BACKGROUND: The etiology of the inflammatory ON is multifactorial. Much attention is paid to the inflammatory and immune processes that are likely to contribute to the demyelination and MS development. IL-6, VEGFA, and TIMP-3 genes are thought to be involved in the inflammatory processes and manifestation of CNS demyelination, so we aimed to determine the relationship between VEGFA rs1413711, TIMP-3 rs9621532,...

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Source

Identifiers

PMID: 33121296
DOI: 10.1080/13816810.2020.1839916

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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