Article
Relationship between rs4349859 and rs116488202 polymorphisms close to MHC-I region and serum urate levels in patients with gout.
Molecular biology reports - 1 May 2023
Fernández-Torres Javier, Zamudio-Cuevas Yessica, Martínez-Nava Gabriela Angélica, Martínez-Flores Karina, Ruíz-Dávila Xiadani, Sánchez-Sánchez Roberto
Abstract excerpt
BACKGROUND: Gout is the most common inflammatory rheumatic disease and elevated levels of serum urate (SU) are the main cause for its development. Major histocompatibility complex class 1 (MHC-1) plays an important role in the development of multiple inflammatory diseases; however, there is little evidence of its involvement in gout. The present study focused on evaluating the association of the rs4349859 and...
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