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Article

The interplay between HLA-B and NLRP3 polymorphisms may be associated with the genetic susceptibility of gout.

Molecular biology reports - 1 Nov 2022

Fernández-Torres Javier, Martínez-Nava Gabriela Angélica, Martínez-Flores Karina, Sánchez-Sánchez Roberto, Jara Luis J, Zamudio-Cuevas Yessica

Abstract excerpt

BACKGROUND: HLA and NLRP3 play an important role in the development of various autoimmune and autoinflammatory diseases. Gout is an autoinflammatory disease associated with multiple genetic and environmental factors. The objective of the present study was to evaluate the interaction and association between genetic polymorphisms of HLA-B and the NLRP3 gene in Mexican patients with gout. METHODS AND RESULTS:...

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Identifiers

PMID: 36057006
DOI: 10.1007/s11033-022-07895-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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