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Article

HLA-B leader genotypes in a clinical population.

HLA - 1 Jul 2023

Balgansuren Gansuvd, Sprague Maggie, Peterson Paula, Shenavar Yasaman, Ng Ada, Regen Lois, Shelton Nakita, Petersdorf Effie

Abstract excerpt

The -21 dimorphism in the leader sequences of HLA-B exon 1 is associated with risk of graft-versus-host disease (GVHD), relapse and overall survival after unrelated donor hematopoietic cell transplantation (HCT), haploidentical HCT and cord blood transplantation. Consideration of the leader dimorphism in the prospective selection of allogeneic donors for HCT may help to lower risks for patients, but requires...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36929133
DOI: 10.1111/tan.15022
PMCID: PMC13387073

Genes

C2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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