Article
Frequency and Distribution of KIR Genotypes of Donors-Recipient Pairs in the Haploidentical Haematopoietic Stem Cell Transplantation Setting: Collaborative Study by the Spanish Working Group in Histocompatibility and Transplant Immunology (GETHIT) and the Spanish Haematopoietic Transplantation and Cell Therapy Group (GETH-TC).
HLA - 1 May 2025
Luis-Hidalgo Mar, Planelles Dolores, Piñana José Luis, Carbonell Juan, Amat Paula, Gómez-Seguí Inés, Guerreiro Manuel, Caballero Abelardo, Torío Alberto, Pascual-Cascón Mª Jesús, Boix Francisco, Marín Rubio Luis, Vázquez Lourdes, Martínez-Pomar Natalia, Cunill Vanesa, Sampol Antonia, Ochoa Julio, Arbona Cristina, Solano Carlos
Abstract excerpt
There is limited information regarding the influence of KIR genotype, compared to the HLA system, in haploidentical haematopoietic stem cell transplantation (haplo-HSCT). This study aimed to determine the frequencies of KIR genotypes in Spanish haematologic patients undergoing haplo-HSCT. A study was conducted on 113 oncohaematological patients and their donors, treated across five centres that are members of the...
Read the complete abstract on PubMedTopics
- Humans
- Receptors, KIR
- Hematopoietic Stem Cell Transplantation