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Article

Curcumin-dependent phenotypic transformation of microglia mediates resistance to pseudorabies-induced encephalitis.

Veterinary research - 14 Mar 2023

Feng Luqiu, Luo Guodong, Li Yuhang, Zhang Chen, Liu Yuxuan, Liu Yanqing, Chen Hongyue, He Daoling, Zhu Yan, Gan Ling

Abstract excerpt

Pseudorabies virus (PRV) causes viral encephalitis, a devastating disease with high mortality worldwide. Curcumin (CUR) can reduce inflammatory damage by altering the phenotype of microglia; however, whether and how these changes mediate resistance to PRV-induced encephalitis is still unclear. In this study, BV2 cells were infected with/without PRV for 24 h and further treated with/without CUR for 24 h. The...

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Source

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Identifiers

PMID: 36918933
DOI: 10.1186/s13567-023-01149-x
PMCID: PMC10015794

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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