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Article

Physical Frailty, Genetic Predisposition, and Incident Parkinson Disease.

JAMA neurology - 1 May 2023

Zheng Zekun, Lv Yanling, Rong Shuang, Sun Taoping, Chen Liangkai

Abstract excerpt

Importance: Cross-sectional evidence implicates high prevalent frailty in patients with Parkinson disease (PD), whereas the longitudinal association remains unknown. Objectives: To examine the longitudinal association of the frailty phenotype with the development of PD and to explore the modification role of genetic risk of PD in such an association. Design, Setting, and Participants: This prospective cohort...

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Aged
Cross-Sectional Studies
Dementia
Frail Elderly
Frailty
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Parkinson Disease

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Identifiers

PMID: 36912851
DOI: 10.1001/jamaneurol.2023.0183
PMCID: PMC10012040

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