Article
Physical frailty, genetic predisposition, and the risks of severe non-alcoholic fatty liver disease and cirrhosis: a cohort study.
Journal of cachexia, sarcopenia and muscle - 1 Aug 2024
Yang Honghao, Ou Fengrong, Chang Qing, Jiang Jinguo, Liu Yashu, Ji Chao, Chen Liangkai, Xia Yang, Zhao Yuhong
Abstract excerpt
BACKGROUND: Frailty, defined as a phenotype of decreased physiological reserves and diminished ability to respond to stressors, has been linked to the development of chronic diseases. Epidemiological evidence connecting frailty to non-alcoholic fatty liver disease (NAFLD) and cirrhosis risks remain sparse. We aimed to assess the longitudinal associations of frailty with the risks of severe NAFLD and cirrhosis in...
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