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Article

Association of SNPs in the PAI1 Gene with Disease Recurrence and Clinical Outcome in Bladder Cancer.

International journal of molecular sciences - 3 Mar 2023

Murakami Kaoru, Furuya Hideki, Hokutan Kanani, Goodison Steve, Pagano Ian, Chen Runpu, Shen Cheng-Huang, Chan Michael W Y, Ng Chi Fai, Kobayashi Takashi, Ogawa Osamu, Miyake Makito, Thornquist Mark, Shimizu Yoshiko, Hayashi Kazukuni, Wang Zhangwei, Yu Herbert, Rosser Charles J

Abstract excerpt

PURPOSE: Bladder cancer (BCa) is one of the most common cancer types worldwide and is characterized by a high rate of recurrence. In previous studies, we and others have described the functional influence of plasminogen activator inhibitor-1 (PAI1) in bladder cancer development. While polymorphisms in PAI1 have been associated with increased risk and worsened prognosis in some cancers, the mutational status of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36902377
DOI: 10.3390/ijms24054943
PMCID: PMC10003630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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