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Article

Association between Five Common Plasminogen Activator Inhibitor-1 (PAI-1) Gene Polymorphisms and Colorectal Cancer Susceptibility.

International journal of molecular sciences - 18 Jun 2020

Oh Jisu, An Hui Jeong, Kim Jung Oh, Jun Hak Hoon, Kim Woo Ram, Kim Eo Jin, Oh Doyeun, Kim Jong Woo, Kim Nam Keun

Abstract excerpt

The plasminogen activator inhibitor-1 (PAI-1) is expressed in many cancer cell types and modulates cancer growth, invasion, and angiogenesis. The present study investigated the association between five PAI-1 gene polymorphisms and colorectal cancer (CRC) risk. Five PAI-1 polymorphisms (-844G > A [rs2227631], -675 4G > 5G [rs1799889], +43G > A [rs6092], +9785G > A [rs2227694], and +11053T > G [rs7242]) were...

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Identifiers

PMID: 32570732
DOI: 10.3390/ijms21124334
PMCID: PMC7352892

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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