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Article

Renin-Angiotensin System Single Nucleotide Polymorphisms Are Associated with Bladder Cancer Risk.

Current oncology (Toronto, Ont.) - 15 Nov 2021

Samara Maria, Papathanassiou Maria, Farmakioti Ioanna, Anagnostou Maria, Satra Maria, Mitrakas Lampros, Anastasiou Dimitrios, Chasiotis Georgios, Christopoulos Agamemnon, Anagnostou Athanasios, Christodoulou Anastasios, Daponte Alexandros, Ioannou Maria, Koukoulis George, Tzortzis Vassilios, Vlachostergios Panagiotis J

Abstract excerpt

The renin-angiotensin system (RAS), besides being a major regulator of blood pressure, is also involved in tumor angiogenesis. Emerging evidence suggests a correlation between the use of pharmacologic RAS inhibitors and a delay in urothelial bladder cancer (BC) progression. However, it is unknown whether RAS gene variants may predispose to the development of BC. This study examined the association of RAS single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34898568
DOI: 10.3390/curroncol28060396
PMCID: PMC8628720

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