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Article

The role of CDK8 gene polymorphisms in bladder cancer susceptibility and prognosis: a study in the Chinese Han population.

BMC cancer - 16 Apr 2025

Li Zhilong, Su Min, Li Qin, Zheng Xuelian, Song Yaping, Wang Yanyun, Zhou Bin, Zhang Lin

Abstract excerpt

BACKGROUND: Cyclin-dependent kinase 8 (CDK8) has been implicated in various tumors, with its role differing across tumor types. However, the association between CDK8 polymorphisms and bladder cancer (BC) remains unclear. This study investigated the association between CDK8 polymorphisms and BC susceptibility and prognosis. METHODS: This case-control study included 271 patients with BC and 381 healthy controls....

Read the complete abstract on PubMed

Topics

Adult
Aged
Female
Humans
Male
Middle Aged
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

China

Cyclin-Dependent Kinase 8

Genetic Predisposition to Disease

Genotype

Polymorphism, Single Nucleotide

Prognosis

Urinary Bladder Neoplasms

East Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 40241036
DOI: 10.1186/s12885-025-14132-w
PMCID: PMC12004600

Genes

CDK8
IMPACT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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