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Defective chaperone-mediated autophagy is a hallmark of joint disease in patients with knee osteoarthritis

7 Mar 2023

Abstract excerpt

OBJECTIVE: Defects in autophagy contribute to joint aging and Osteoarthritis (OA). Identifying specific autophagy types could be useful for developing novel treatments for OA. DESIGN: An autophagy-related gene array was performed in blood from non-OA and knee OA subjects from the Prospective Cohort of A Coruña (PROCOAC). The differential expression of candidate genes was confirmed in blood and knee cartilage and...

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PMID: 36893980
DOI: 10.1016/j.joca.2023.02.076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

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