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SWI/SNF-type complexes–transcription factor interplay: a key regulatory interaction

10 Mar 2025

Abstract excerpt

ATP-dependent switch/sucrose nonfermenting-type chromatin remodeling complexes (SWI/SNF CRCs) are multiprotein machineries altering chromatin structure, thus controlling the accessibility of genomic DNA to various regulatory proteins including transcription factors (TFs). SWI/SNF CRCs are highly evolutionarily conserved among eukaryotes. There are three main subtypes of SWI/SNF CRCs: canonical (cBAF), polybromo...

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PMID: 40065228
DOI: 10.1186/s11658-025-00704-y

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