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Genome-guided manipulation of regulators of morphogenesis in a <i>C. albicans</i> strain with low virulence is not sufficient to trigger a high-virulence phenotype

2025-07-17

Abstract excerpt

As a member of the microbiome, C. albicans colonizes the oral cavity and other mucosal surfaces of the human body. While commensalism is tightly controlled by the host immune system, the fungal determinants enabling the fungus to colonize the host mucosa without causing tissue damage and inflammation remain less clear. In search of genetic determinants that may underly the commensal lifestyle of the low-virulent...

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Literature Corpus work
2a935417-6c09-58fe-aa7d-a4e19e03b890
DOI
10.1101/2025.07.16.665085
Open publication

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Genome-guided manipulation of regulators of morphogenesis in a <i>C. albicans</i> strain with low virulence is not sufficient to trigger a high-virulence phenotypeDOI 10.1101/2025.07.16.665085
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