Article
Manipulation of regulators of morphogenesis is not sufficient to render a Candida albicans colonizer strain pathogenic.
mBio - 13 May 2026
Fróis-Martins Ricardo, Mertens Sarah, Tran Van Du T, Maufrais Corinne, d'Enfert Christophe, Sanglard Dominique, LeibundGut-Landmann Salomé
Abstract excerpt
As a member of the microbiome, Candida albicans colonizes the oral cavity and other mucosal surfaces of the human body. While commensalism is tightly controlled by the host immune system, the fungal determinants enabling the fungus to colonize the host mucosa without causing tissue damage and inflammation remain less clear. In search of genetic determinants that may underlie the commensal lifestyle of the...
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