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Article

Somatic mutation landscape in a cohort of meningiomas that have undergone grade progression.

BMC cancer - 7 Mar 2023

Cain Sarah A, Pope Bernard, Mangiola Stefano, Mantamadiotis Theo, Drummond Katharine J

Abstract excerpt

BACKGROUND: A subset of meningiomas progress in histopathological grade but drivers of progression are poorly understood. We aimed to identify somatic mutations and copy number alterations (CNAs) associated with grade progression in a unique matched tumour dataset. METHODS: Utilising a prospective database, we identified 10 patients with meningiomas that had undergone grade progression and for whom matched pre-...

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Identifiers

PMID: 36882706
DOI: 10.1186/s12885-023-10624-9
PMCID: PMC9990218

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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