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Article

PNPLA3 genotypes modify the adverse effect of the total energy intake on high-risk nonalcoholic steatohepatitis development.

The American journal of clinical nutrition - 1 May 2023

Son Heejun, Koo Bo Kyung, Joo Sae Kyung, Lee Dong Hyeon, Jang Heejoon, Park Jeong Hwan, Chang Mee Soo, Kim Won

Abstract excerpt

BACKGROUND: The relationship between diet and risk genotypes in nonalcoholic steatohepatitis (NASH) development and fibrosis progression in patients with nonalcoholic fatty liver disease (NAFLD) remains unclear. OBJECTIVE: We aimed to investigate the effects of diet on NASH development and fibrosis progression in patients with NAFLD stratified by the PNPLA3 genotype. METHODS: We performed a prospective study in a...

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PMID: 36878430
DOI: 10.1016/j.ajcnut.2023.02.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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