Article
PNPLA3 GENE POLYMORPHISM AND RED MEAT CONSUMPTION INCREASED FIBROSIS RISK IN NASH BIOPSY-PROVEN PATIENTS UNDER MEDICAL FOLLOW-UP IN A TERTIARY CENTER IN SOUTHWEST BRAZIL.
Arquivos de gastroenterologia - 1 Jan 2000
Yoshimura Silvia Massami, Duarte Sebastião Mauro Bezerra, Stefano José Tadeu, Mazo Daniel Ferraz de Campos, Pinho João Renato Rebello, Oliveira Claudia P
Abstract excerpt
BACKGROUND: Recent studies show an increase in nonalcoholic fatty liver disease (NAFLD) in populations with higher consumption of red meat, processed and cooked at high temperatures. On the other hand, the single nucleotide polymorphism rs738409 in the Patatin-like phospholipase domain containing 3 (PNPLA3) gene has been implicated in susceptibility to NAFLD and liver fibrosis. However, the synergistic effect...
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