Article
Lymphocyte Crossmatch Testing or Donor HLA-DP and -DQ Allele Typing Effectiveness in Single Cord Blood Transplantation for Patients With Anti-HLA Antibodies Other Than Against HLA-A, -B, -C, and -DRB1.
Transplantation and cellular therapy - 1 Jul 2024
Osada Makoto, Yamamoto Hisashi, Watanabe Otoya, Yamaguchi Kyosuke, Kageyama Kosei, Kaji Daisuke, Taya Yuki, Nishida Aya, Ishiwata Kazuya, Takagi Shinsuke, Makino Shigeyoshi, Asano-Mori Yuki, Yamamoto Go, Taniguchi Shuichi, Wake Atsushi, Uchida Naoyuki
Abstract excerpt
Anti-human leukocyte antigen (HLA) antibodies other than those against HLA-A, -B, -C, and DRB1 are a risk factor for engraftment delay and failure, especially in cord blood transplantation (CBT). The primary objective of this study was to assess the impact of the presence of anti-HLA antibodies on CBT and to evaluate the utility of lymphocyte crossmatch testing or additional HLA-DP and -DQ typing of CB units in...
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