Article
Birthweight, BMI in adulthood and latent autoimmune diabetes in adults: a Mendelian randomisation study.
Diabetologia - 1 Sept 2022
Wei Yuxia, Zhan Yiqiang, Löfvenborg Josefin E, Tuomi Tiinamaija, Carlsson Sofia
Abstract excerpt
AIMS/HYPOTHESIS: Observational studies have found an increased risk of latent autoimmune diabetes in adults (LADA) associated with low birthweight and adult overweight/obese status. We aimed to investigate whether these associations are causal, using a two-sample Mendelian randomisation (MR) design. In addition, we compared results for LADA and type 2 diabetes. METHODS: We identified 43 SNPs acting through the...
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