Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linking individual variability in functional brain connectivity to polygenic risk in major depressive disorder.

Journal of affective disorders - 15 May 2023

Hou Zhuoliang, Jiang Wenhao, Li Fan, Liu Xiaoyun, Hou Zhenghua, Yin Yingying, Zhang Haisan, Zhang Hongxing, Xie Chunming, Zhang Zhijun, Kong Youyong, Yuan Yonggui

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) is a highly heterogeneous disease, which brings great difficulties to clinical diagnosis and therapy. Its mechanism is still unknown. Prior neuroimaging studies mainly focused on mean differences between patients and healthy controls (HC), largely ignoring individual differences between patients. METHODS: This study included 112 MDD patients and 93 HC subjects....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Glands
Share to Depressive Disorder, Major

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypothalamus

Share to Neural Pathways

Share to Norepinephrine

Share to Pituitary Gland

Share to Prefrontal Cortex

Share to Serotonin

Source

Identifiers

PMID: 36842648
DOI: 10.1016/j.jad.2023.02.104

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linking individual variability in functional brain connectivity to polygenic risk in major depressive disorder.PMID 36842648Read ↗

Genotype-stratified Default Mode Network hyperconnectivity in major depressive disorder: an MR imaging genetics study.Semantic proximity Read ↗

Multi-scale neural signatures of major depressive, anxiety, and stress-related disordersSemantic proximity Read ↗

Mapping Neurophysiological Subtypes of Major Depressive Disorder Using Normative Models of the Functional ConnectomeSemantic proximity Read ↗

ENIGMA MDD: Seven Years of Global Neuroimaging Studies of Major Depression through Worldwide Data SharingSemantic proximity Read ↗

Association between polygenic risk for Major Depression and brain structure in a mega-analysis of 50,975 participants across 11 studies.Semantic proximity Read ↗

Unique genetic and risk-factor profiles in multimorbidity clusters of depression-related disease trajectories from a study of 1.2 million subjectsSemantic proximity Read ↗

Correlation between polygenic risk scores of depression and cortical morphology networks.Semantic proximity Read ↗

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).Semantic proximity Read ↗

Brain structural connectivity, anhedonia, and phenotypes of major depressive disorder: A structural equation model approach.Semantic proximity Read ↗

Phenotype Network and Brain Structural Covariance Network of Major Depression.Semantic proximity Read ↗

Depression polygenic risk-linked multimodal MRI network and associated cognitive dysfunction.Semantic proximity Read ↗

Dissecting biological heterogeneity in major depressive disorder based on neuroimaging subtypes with multi-omics dataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.