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Article

Nucleos(t)ide analogues altered quasispecies composition of hepatitis B virus (HBV)-resistant mutations in serum HBV DNA and serum HBV RNA.

Journal of medical virology - 1 Mar 2023

Liao Hao, Zhang He, Shao Jinman, Li Xiaoyong, Zheng Wei V, Li Le, Yu Guangxin, Si Lanlan, Zhou Tao, Yao Zengtao, Dai Jiuzeng, Xu Dongping, Cheng Guanxun, Qu Jiuxin, Liu Yan, Chen Junhui, Lu Fengmin

Abstract excerpt

Serum hepatitis B virus (HBV) RNA is a new serological indicator reflecting viral replication with good clinical application prospects. This study aimed to clarify the dynamic changes of serum HBV RNA levels and the quasispecies of HBV RNA virus-like particles in nucleos(t)ide analogues (NAs)-experienced chronic hepatitis B (CHB) patients harboring NAs-resistant mutations and their identifiable effects on NAs...

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Share to Antiviral Agents
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36840474
DOI: 10.1002/jmv.28612

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