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Article

Cellular Senescence as a Target in Cancer Control

30 Dec 2010

Abstract excerpt

Somatic cells show a spontaneous decline in growth rate in continuous culture. This is not related to elapsed time but to an increasing number of population doublings, eventually terminating in a quiescent but viable state termed replicative senescence. These cells are commonly multinucleated and do not respond to mitogens or apoptotic stimuli. Cells displaying characteristics of senescent cells can also be...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 21234095
DOI: 10.4061/2011/725365

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